• br Results br Expression profiles of circRNAs in NOT

  2022-05-07

  

  3. Results 3.1. Expression profiles of circRNAs in NOT and EOC To investigate circRNAs function in NOT and EOC, we firstly ex-amined the dysregulated circRNAs via RNA sequencing. Three NOT from cervical cancer patients underwent prophylactic oophorectomy, and three EOC were sequenced and ana

• br Bone scans provide information on cancers that have

  2022-05-07

  

  Bone scans provide information on cancers that have metastasized into skeletal structures. Pre-treatment metastases are important to identify, as stage dictates the appropriate treatment and provides prognosis for a patient. Bone scans were documented in diffuse sites in the EHRs: as structured da

• br caption on next page

  2022-05-06

  

  (caption on next page) Fig. 3. Combining ADD with CpG and αPD-1 increased cytotoxic T lymphocytes in local and distant NDL tumors. A) Representative treatment protocol and timeline for treatment of NDL tumor-bearing mice. One tumor of bilateral tumors of NDL orthotopically transplanted into FVB

• br This study aims at improving combinational

  2022-05-04

  

  This study aims at improving combinational therapy with siRNA and anticancer chemotherapy drugs. The anticancer drug used in this study is etoposide which is representative of many other hydrophobic anti-cancer drugs with poor bioavailability, low solubility and high resistance (Nitiss, 2009; Wang

• br Experimental br For production of Au high purity

  2022-04-29

  

  2. Experimental For production of 198Au, high purity gold foil was used which was procured from Roviur International, Singapore. Cyclic (arginine-glycine-aspartate-phenylalanine-lysine) [c(RGDfK)] peptide was ob-tained from ABX Advanced Biochemical Compounds, Germany. All other chemicals were o

• br Scheme Structure based bioisosterism design of

  2022-04-28

  

  Scheme 2. Structure-based bioisosterism design of target 1,4-naphthoquinone-1,2,3-triazole hybrid compounds. Table 1 Reaction optimization for synthesis of compound 6a. Compound Solventa ArCH2N3 (equiv) Temp (°C) Yield (%) 6a H2O/t-BuOH 1.0 rt Trace The desired 1,4-naphthoqui

• Sorafenib br DMSO TPA br Levels

  2022-04-28

  

  DMSO TPA Levels 12 Protein Claudin 1 8 Relative 4 β-actin DMSO TPA Levels 3 Claudin 1 Protein 2 β-actin Relative DMSO TPA Levels 4 TPA Protein 3 Control Claudin 1 Relative D: MDCKII DMSO TPA Control Claudin 1 Protein 1 T

• br Size and zeta potential br Hydrodynamic

  2022-04-28

  

  2.2. Size and zeta potential Hydrodynamic diameter and zeta potential of NPs was measured with a Zetasizer ZS90 (Malvern®). Briefly, 100 μL of NPs were placed in polystyrene disposable Epoprostenol and brought to 1 mL with PBS (pH 7.4) followed by gentle mixing. Each sample was measured at 90°

• br Circulating mtDNA as diagnostic and

  2022-04-28

  

  1216 Circulating mtDNA as diagnostic and prognostic biomarker in EOC Meng et al. Translational Oncology Vol. 12, No. 9, 2019 samples of 90 German and 75 Chinese patients with EOC, and 60 age-matched healthy women by a NanoDrop Spectrophotometer and SYBR qRT-PCR, respectively. The amplification

• br Figure Repression of hsa

  2022-04-27

  

  Figure 1 Repression of hsa_circ_0007059 was exhibited in lung cancer tissues (A) The tumor tissues and adjacent tissues from a total of 20 patients with lung cancer were gathered, RT-qPCR assay was implemented for the evaluation of hsa_circ_0007059 expression. (B) The tumor tissues from the fiv

• br Results br CircNR C is down

  2022-04-27

  

  3. Results 3.1. CircNR3C1 is down-regulated in KIN59 cancer tissues and cell lines, and mainly localizes in cytoplasm According to the RNA-seq data [23], we found that circNR3C1, which is named hsa_circ_0001543 in CircBase (http://www.circbase. org/), was down-regulated in bladder cancer ti

• br Fig Cr VI regulates cell migration

  2022-04-27

  

  Fig. 5. Cr(VI) regulates cell migration via promoting the EMT. A. The mRNA expression of E-cadherin, N-cadherin and Snail in PC3 CCK8 exposed to Cr(VI) for 48 h (n = 6). B. Western bolt analyses of the protein levels of E-cadherin, N-cadherin and Snail in PC3 cells exposed to Cr(VI) for 48 h.

• br For determination of total selenium content g of sample

  2022-04-26

  

  For determination of total selenium content, 0.2 g of sample was mixed with 4 mL of HNO3 77% (SCP science, Canada) and the resulting mixture was digested in sealed containers using a microwave oven (Mars 5 CEM, Matthews, NC). The selenium content in resulting Trichostatin A hydrolysates was measur

• br Baade PD Youlden DR Andersson TM Youl PH Walpole

  2022-04-24

  

  7. Baade PD, Youlden DR, Andersson TM, Youl PH, Walpole ET, Kimlin MG, et al. Temporal changes in loss of life expectancy due to cancer in Australia: Prostaglandin J2 flexible parametric approach. Cancer Causes Control 2016; 27: 955-964. 9. Syriopoulou E, Bower H, Andersson TM, Lambert PC, Ruth

• Heparin br Fig A The SDS

  2022-04-24

  

  Fig. 3. A) The SDS-PAGE images of the gel after Coomassie blue staining. Lane 1: molecular markers; Lane 2: Cetuximab only; Lane 3: Dox-NPs (negative control); Lane 4: Dox-NPs-Cet. B) The stability of Dox-NPs-Cet in 0.01M Tris-HCl (pH7.4) at two different temperatures. Fig. 4, Dox-NPs-Cet were

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