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br M In vivo imaging
2019-10-14
(M) In vivo imaging of tumor vasculature of KPf/fC mice treated with vehicle or SR2211. Vasculature is marked by in vivo delivery of anti-VE-Cadherin (magenta), scale = 75um. Figure S7. Analysis of Downstream Targets of RORg in Murine and Human Pancreatic Cancer Cells Identifies Shared Pro-tumo
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br Figure Reader data collection Microsoft
2019-10-14
Figure 2. Reader data collection. Microsoft Access-designed application used to collect data from each reader. All patient sequence IDs and names are anonymized, and all 135 sequences appeared in random order to the reader. Readers could identify up to four lesions per sequence, and gave lesion
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br Breast cancer is the most
2019-10-10
Breast cancer is the most frequently diagnosed cancer (25% of all female cancers) and the leading cause of cancer deaths among women, resulting in nearly 1.7 million new cases diagnosed world-wide in 2012 [1]. Breast cancer is also the second leading cause of cancer deaths in U.S. women. About one
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br Introduction br In recent times
2019-10-07
Introduction In recent times, folate receptor (FR) based cancer targeting and therapeutic study become very thought-provoking as FRs are over-expressed in many of epithelial-derived human cancer cells and the same are minimally expressed in normal human cells [1–5]. Folic Oxidopamine hydrochlor
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c NUS Graduate School of Integrative Sciences and Engineerin
2019-10-03
c NUS Graduate School of Integrative Sciences and Engineering, NUS, Singapore d Cancer Science Institute, NUS, Singapore e Department of Biological Sciences, National University of Singapore (NUS), Singapore f Department of Otolaryngology, National University Healthcare System (NUHS), Singapore
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br J Bouchal The role of
2019-10-02
J. Bouchal, The role of cancer-associated fibroblasts, solid stress and other micro-environmental factors in tumor progression and therapy resistance, Cancer Cell Int. 14 (2014) 41. anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxi
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br The concentrations of cancer biomarkers
2019-10-01
The concentrations of cancer biomarkers are usually high in can-cerous blood samples. Evaluation of cancer biomarkers, which include Corresponding author. E-mail address: [email protected] (M. Mazloum-Ardakani). different types of molecules such as proteins, has been the most widely us
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br Fig Forest plots of multivariable hazard ratios
2019-09-27
Fig. 3. Forest plots of multivariable hazard ratios with 95% confidence intervals for LDR boost (left) and DE-EBRT (right) against HDR boost as baseline for specific subgroups. p (int) represents p-values for the interaction terms. DE-EBRT 5 dose-escalated external beam radiation therapy; HDR 5 hi
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br References br Alanko A
2019-09-26
References [2] Alanko A, Heinonen E, Scheinin T, et al. Significance of estrogen and progesterone receptors, disease-free interval, and site of first metastasis on survival of breast cancer patients. Cancer 1985;56:1696-700 [PMID: 4027900]. [8] Lewis GH, Subhawong AP, Nassar H, et al. Rel
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br Related work br Recent histological tissue segmentation t
2019-09-24
2. Related work Recent histological tissue segmentation techniques can be split into two groups based on the nature of the features upon which they rely. In the first group we find methods based on feature en-gineering, with features linked either to pixel-/patch- level infor-mation (Doyle, Fel
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SCH 58261 br Among the cases we observed no evidence that se
2019-09-23
Among the cases, we observed no evidence that serum PBDE con-centrations varied by the time interval between diagnosis and blood draw. There was no correlation between PBDE serum levels and the time interval between diagnosis and blood draw (Spearman Rank cor-relations ranged from −0.1 to 0.05 and
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br Drug likeness properties prediction
2019-09-21
3.2. Drug-likeness properties prediction Drug-likeness properties calculation indicated that all the proposed compounds could be successful oral drug candidates, as they had no violation of Lipinski and Veber rules (Lipinski et al., 1997; Veber et al., 2002). As mentioned in Table 1, the compou
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br Animal xenograft model br The
2019-09-16
2.11. Animal xenograft model The exponentially growing A2780/Taxol Epirubicin HCl were harvested and washed twice with PBS. 5 × 106 cells were resuspended in PBS/ma-trigel (1:1) and injected subcutaneously into the right axilla of mice. When tumor volume reached 80-100 mm3, mice were divided in
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br These findings are further supported by the observation
2019-09-16
These findings are further supported by the observation that 24R,25(OH)2D3 inhibited expression of metastatic markers, including expression of Snail, Her2, and collagenase, as well as the ratio of CXCR4 to CXCL12. Migration was inhibited in a dose-dependent manner when testing wound closure using
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br Western blot analysis br Proteins
2019-09-16
2.4. Western blot analysis Proteins were resolved by SDS-polyacrylamide gel electrophoresis, transferred onto a PVDF membrane and detected using the appropriate primary and secondary o-Phenanthroline before visualization with a chemi-luminescence kit (Biological Industries, Beit- Haemek, Israe