• br CYP gene is located in

  2020-08-18

  

  CYP19 gene is located in the chromosome 15q21.2 contains ten Abbreviations: PCR, polymerase chain reaction; CYP19, cytochrome P45 19 gene; EC, endometrial cancer; OC, ovarian cancer; OR, odds ratio Corresponding author. E-mail address: [email protected] (A.I. Al-Badran). e

• br Another important finding of the present study is that

  2020-08-18

  

  Another important finding of the present study is that muscle and skin metastases were associated with a lower response rate to first-line therapy. There are several possible explanations for the lower responsiveness among patients with these metastases. First, the tumor burden may be related to t

• br of transcription B Conclusion Our

  2020-08-14

  

  of transcription 5B. Conclusion: Our results suggested that a stronger combined effect of SNPs in RANKL, OPG, CHI3L1, and VDR SQ109 via geneegene interaction may help predict BC risk and prognosis. Keywords: Epistasis, Geneegene interaction, Haplotype, Metastasis, Polymorphism 1Medical Bioc

• pattern for total cancer incidence because the

  2020-08-14

  

   pattern for total cancer incidence because the individuals using 180e360 DDD sedative-hypnotics showed the highest HR for overall cancer. It is possible that the use of extreme levels of sed-atives might result in different health outcomes such as death. Lastly, in this analysis, we used prescrip

• Pentostatin br Statistical analysis br Statistical

  2020-08-12

  

  2.10. Statistical analysis Statistical significance was determined with the unpaired Student's t-test for two-group comparison and two-way ANOVA for multiple-group analysis performed with GraphPad Prism 6.00; differences be-tween groups have been considered significant at a p value of b0.05.

• br Gottingen Germany br Nu Nu mice were intraperitoneally in

  2020-08-12

  

  Gottingen,€ Germany). Nu/Nu mice were intraperitoneally injected with 1 106 SKOV3-Luc cells to form tumors. After 5 days, BMS-777607 (50 mg/ kg daily) or an equal volume of water (control) was administered orally to these tumor-bearing mice. The tumor growth was moni-tored in terms of luminesce

• br The quantification of ML and VT

  2020-08-12

  

  The quantification of ML and VT contents in the preparation are detailed by Pfüller and Schumacher (2016). Iscucin® Salicis and Tiliae delivered high, Crataegi, Populi and Mali middle and Abietis and Pini low content of ML-1, analysed by ELISA. A high value of VT-A was mea-sured in Iscucin® Cratae

• S Kossatz J Grandke P Couleaud A Latorre

  2020-08-12

  

  [30] S. Kossatz, J. Grandke, P. Couleaud, A. Latorre, A. Aires, K. Crosbie-Staunton, R. Ludwig, H. Dähring, V. Ettelt, A. Lazaro-Carrillo, Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery, Br

• br Discussion br This study

  2020-08-12

  

  Discussion This study sought to identify genes potentially co-expressed with the cyclin E oncogene in gastric Table 4 Top 19 genes with highest connectivity in predicted interaction network. Gene Symbol Connectivity (Degree) Pearson Co. Spearman Co. Pearson Co.: Pearson correlati

• br Fig Effect of the protein fraction

  2020-08-12

  

  Fig. 5. Effect of the protein fraction on expression of Bcl-2, Bax and caspase-3 of MDA-MB-231 cells. (A) Immunoblots show dose dependent WSPF induced down regulation of Bcl-2 and up-regulation of Bax and cleaved caspase-3 protein. (B) Densitometry analysis of expression of apoptosis related prote

• br de la Puente P

  2020-08-07

  

  160. de la Puente P, Luderer MJ, Federico C, et al. Enhancing proteasome-inhibitory activity and specificity of bortezomib by CD38 targeted nanoparticles in multiple myeloma. Journal of controlled release : official journal of the Controlled Release Society. Jan 28 2018;270:158-176. 162. Huang

• br References br M V Mandke H

  2020-08-07

  

   References [10] M.V. Mandke, H.M. Pathan, Electrochemical growth of copper nanoparticles: structural and optical properties, J. Electroanal. Chem. 686 (2012) 19–24. [11] K. Mohan Kumar, M. Badal Kumar, H.A. Kiran Kumar, M. Sireesh Babu, Green synthesis of size controllable gold nanoparticle

• br Combinatory approach in cancer treatment br Tumors

  2020-08-07

  

  4.3. Combinatory approach in cancer treatment Tumors exhibit heterogeneous, irregular and branched blood vessel network (Nagy et al., 2010). These heterogeneity in vascularization resulted in permeability imbalances and inadequate blood supply to differential compartments of the tumor tissue fur

• br Active DUB labeling assays br Active

  2020-08-06

  

  2.7. Active DUB labeling assays Active DUB labeling assays was performed as previously described (Liu et al., 2014). Briefly, 22RV1 cck-8 were treated with Aur for 24 h and the lysates were incubated with HA-UbVS for 1 h at 37 °C, which was followed by boiling in reducing sample buffer. Sampl

• br Shorter OS in patients with higher number of

  2020-08-06

  

  3.2. Shorter OS in patients with higher number of metastatic organs The KaplaneMeier survival curves showed a significant as-sociation between OS and the M factor status (p¼0.0306) (Fig. 1A). The number of metastatic organs was also signifi-cantly related to OS (p¼0.0001) (Fig. 1B); the median

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